Gastroenterology Education and CPD for trainees and specialists » NSAIDS GI toxicity https://www.gastrotraining.com Largest online gastroenterology, hepatology and endoscopy education and training resource with histology, x-ray images, videos, gastro calculators, and MCQs. Thu, 04 Dec 2025 21:29:42 +0000 en-US hourly 1 http://wordpress.org/?v= NSAIDS induced GI mucosal injury https://www.gastrotraining.com/gastro-duodenal/nsaids-gi-toxicity/nsaids-gi-toxicity https://www.gastrotraining.com/gastro-duodenal/nsaids-gi-toxicity/nsaids-gi-toxicity#comments Fri, 30 Jul 2010 12:11:27 +0000 Gastro Training http://www.gastrotraining.com/?p=2017 Elucidate the NSAIDS induced GI toxicity?

Upper GI Small Bowel Colon
GORD

Subepithelial petechial haemorrhage

Erosions

Ulcers(stomach>Duodenum)

Bleeding(stomach=duodenum)

Perforation/obstruction

 Ulcers

Strictures

Diaphragms

Enteropathy

 Colitis

Ulcers

Strictures

Diverticular bleed or perforation

Collagenous colitis

Relapse of IBD

Use of capsule endoscopy has revealed that NSAID plus PPI strategy does not effectively reduce the small bowel lesions that will occur with an NSAID in the small intestine.

12.5% of all GI events which occur with NSAIDs are found in the lower gastrointestinal tract. This proportion of events would not be effectively treated by the NSAID plus PPI strategy.

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