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Intestinal transplantation
Discuss intestinal transplantation?
The intestine is a difficult organ to transplant due to its immunogenicity, large population of donor immune cells present within the graft, and its non sterile contents. Thus intestinal transplantation cannot yet be recommended as an alternative therapy for patients stably maintained on intravenous nutrition.
Intestinal transplantation is currently associated with approximately 80% one year survival and approaching 50% five year survival.
Discuss the current indications for referral of adults to an intestinal transplantation centre in UK?
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