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Upper GI Crohn’s disease

Discuss upper GI Crohn’s disease?

  • Oral Crohn’s disease
    • Aphthous ulcers are the most common feature of Crohn’s disease in the oral cavity.
    • Oral lesions parallel intestinal disease activity and respond to treatment directed at intestinal disease.
    • Topical hydrocortisone or topical sucralfate may provide symptomatic relief.
  • Gastroduodenal Crohn’s disease
    • It is rare and occurs in association with intestinal disease.
    • Gastric antrum and duodenum are most commonly affected.
    • The symptoms include epigastric pain, nausea and vomiting.
    • PPI may provide symptomatic relief. Pentasa is partly released in the proximal small bowel and may theoretically help in duodenal disease.
    • However, steroid is usually necessary and is effective. Immunomodulators may be needed.

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